Complera (emtricitabine / rilpivirine / tenofovir) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Complera (emtricitabine / rilpivirine / tenofovir) which include:
rilpivirine ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
ADJUST DOSING INTERVAL: The administration of rilpivirine in a fasting state may decrease its oral absorption. Under fasted conditions, the systemic exposure to rilpivirine was 40% lower compared to normal or high-fat caloric meals (533 to 928 Kcal). The systemic exposure was 50% lower when rilpivirine was taken with a protein-rich nutritional beverage.
MANAGEMENT: For optimal absorption, it is recommended to take rilpivirine on a regular schedule with a meal.
- "Product Information. Edurant (rilpivirine)." Tibotec Pharmaceuticals, Titusville, NJ.
tenofovir ↔ food
Minor Food Interaction
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For clinical details see professional interaction data.
Complera (emtricitabine / rilpivirine / tenofovir) drug Interactions
There are 543 drug interactions with Complera (emtricitabine / rilpivirine / tenofovir)
Complera (emtricitabine / rilpivirine / tenofovir) disease Interactions
There are 9 disease interactions with Complera (emtricitabine / rilpivirine / tenofovir) which include:
- Renal Dysfunction
- Renal Dysfunction
- Liver Impairment
- Renal Impairment
- Bone Toxicity
- Liver Disease
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
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