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COPD (dyphylline / guaifenesin) and Alcohol / Food Interactions

There is 1 alcohol/food/lifestyle interaction with COPD (dyphylline / guaifenesin):


High Blood Pressure (Hypertension)

Moderate Potential Hazard, Moderate plausibility

dyphylline - cardiotoxicity

Like other methylxanthines, dyphylline at high dosages may be associated with positive inotropic and chronotropic effects on the heart. Therapy with dyphylline and products containing dyphylline should be administered cautiously in patients with severe cardiac disease, hypertension, hyperthyroidism, or recent myocardial infarction. The relationship between plasma dyphylline levels and therapeutic as well as toxic effects has not been determined.


  1. "Multum Information Services, Inc. Expert Review Panel"
  2. "Product Information. Lufyllin (dyphylline)" Wallace Laboratories, Cranbury, NJ.

COPD (dyphylline / guaifenesin) drug interactions

There are 80 drug interactions with COPD (dyphylline / guaifenesin)

COPD (dyphylline / guaifenesin) disease interactions

There are 4 disease interactions with COPD (dyphylline / guaifenesin) which include:

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.