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Diphenhydramine/phenylephrine Interactions

There are 574 drugs known to interact with diphenhydramine/phenylephrine, along with 12 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 40 are major, 531 are moderate, and 3 are minor.

Does diphenhydramine/phenylephrine interact with my other drugs?

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Most frequently checked interactions

View interaction reports for diphenhydramine / phenylephrine and the medicines listed below.

Diphenhydramine/phenylephrine alcohol/food interactions

There are 2 alcohol/food interactions with diphenhydramine / phenylephrine.

Diphenhydramine/phenylephrine disease interactions

There are 12 disease interactions with diphenhydramine / phenylephrine which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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