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Dimercaprol and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with dimercaprol.

Major

dimercaprol multivitamins with minerals

Major Drug Interaction

ADJUST DOSING INTERVAL: Dimercaprol can form a nephrotoxic chelate with certain metals such as cadmium, iron, and selenium.

MANAGEMENT: Preparations containing iron or selenium salts should not be administered during chelation therapy with dimercaprol and for at least 24 hours after the last dose of dimercaprol.

References

  1. Seffart G ed. "Drug Dosage in Renal Insufficiency." Dordrecht, South Holland, : Kluwer Academic Publishers (1991):
  2. Chenoweth MB "Clinical uses of metal-binding drugs." Clin Pharmacol Ther 9 (1968): 365-87
  3. "Product Information. BAL In Oil (dimercaprol)." Apothecon Inc (2022):

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Moderate

High Blood Pressure (Hypertension)

Moderate Potential Hazard, High plausibility

dimercaprol - hypertension

Dose-related increase in systolic and diastolic blood pressure, with or without accompanying tachycardia, is the most frequently reported adverse effect of dimercaprol therapy. Blood pressure may rise 15 to 30 minutes following injection and usually returns to normal within 2 hours. Therapy with dimercaprol should be administered cautiously in patients with hypertension. Clinical monitoring of blood pressure is recommended.

References

  1. "Product Information. BAL In Oil (dimercaprol)." Apothecon Inc (2022):

Dimercaprol drug interactions

There are 28 drug interactions with dimercaprol.

Dimercaprol disease interactions

There are 5 disease interactions with dimercaprol which include:

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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