Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine) and Alcohol / Food Interactions
There is 1 alcohol/food/lifestyle interaction with Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine):
chlorpheniramine ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
- "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
- Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
- "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc, Rockville, MD.
Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine) drug interactions
There are 591 drug interactions with Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine)
Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine) disease interactions
There are 25 disease interactions with Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine) which include:
- impaired GI motility
- infectious diarrhea
- liver disease
- acute alcohol intoxication
- drug dependence
- gastrointestinal obstruction
- intracranial pressure
- respiratory depression
- cardiovascular disease
- anticholinergic effects
- renal/liver disease
- adrenal insufficiency
- biliary spasm
- renal dysfunction
- seizure disorders
- urinary retention
More about Duohist DH (chlorpheniramine / dihydrocodeine / phenylephrine)
- Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.