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Alka-Seltzer PM (aspirin / diphenhydramine) and Alcohol/Food Interactions

There are 3 alcohol/food/lifestyle interactions with Alka-Seltzer PM (aspirin / diphenhydramine) which include:

Minor

aspirin Caffeine

Minor Drug Interaction

Information for this minor interaction is available on the professional version.

Moderate

diphenhydrAMINE Alcohol (Ethanol)

Moderate Drug Interaction

Ask your doctor before using diphenhydrAMINE together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking diphenhydrAMINE. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

aspirin Alcohol (Ethanol)

Moderate Drug Interaction

Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Alka-Seltzer PM (aspirin / diphenhydramine) drug interactions

There are 657 drug interactions with Alka-Seltzer PM (aspirin / diphenhydramine)

Alka-Seltzer PM (aspirin / diphenhydramine) disease interactions

There are 17 disease interactions with Alka-Seltzer PM (aspirin / diphenhydramine) which include:

More about Alka-Seltzer PM (aspirin / diphenhydramine)

Related treatment guides

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.