Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan) and Alcohol / Food Interactions
There are 2 alcohol/food/lifestyle interactions with Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan) which include:
chlorpheniramine ↔ Caffeine
Moderate Drug Interaction
Using chlorpheniramine together with dextromethorphan may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin ↔ Caffeine
Minor Drug Interaction
Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.
For clinical details see professional interaction data.
chlorpheniramine ↔ food
Moderate Food Interaction
Consumer information for this interaction is not currently available.
GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.
MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.
- Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
- "Product Information. Fycompa (perampanel)." Eisai Inc, Teaneck, NJ.
- Gilman AG, Rall TW, Nies AS, Taylor P, eds. "Goodman and Gilman's the Pharmacological Basis of Therapeutics. 8th ed." New York, NY: Pergamon Press Inc. (1990):
- "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc, Rockville, MD.
Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan) drug interactions
There are 1135 drug interactions with Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan)
Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan) disease interactions
There are 14 disease interactions with Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan) which include:
- anticholinergic effects
- GI toxicity
- renal dysfunction
- Reye's syndrome
- renal/liver disease
- psychiatric conditions
- G-6-PD deficiency
More about Alka-Seltzer Plus Flu Formula (old formulation) (aspirin / chlorpheniramine / dextromethorphan)
- Alka-Seltzer Plus Flu Formula (old formulation) Side Effects
- During Pregnancy
- Dosage Information
- Drug Interactions
- Drug class: upper respiratory combinations
- FDA Alerts (1)
Related treatment guides
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.