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Short bowel syndrome

Short bowel syndrome is a condition that occurs when part of the small intestine is missing or has been removed during surgery. Nutrients are not properly absorbed into the body (malabsorption) as a result.

Causes of Short bowel syndrome

When part of the small intestine is missing, there may not be enough surface area in the bowel to absorb enough nutrients from food. The this can happen when half or more of the bowel is removed during surgery or sections are missing due to a birth defect (congenital defect),

Risk factors include diseases of the small intestine that may require surgery, such as Crohn's disease. In infants, necrotizing enterocolitis is a common cause.

Short bowel syndrome Symptoms

Tests and Exams

  • Blood chemistry tests (such as albumin level)
  • Complete blood count (CBC)
  • Fecal fat test
  • Small intestine x-ray
  • Vitamin levels in the blood

Treatment of Short bowel syndrome

Treatment is aimed at relieving symptoms. Treatments may include:

  • A high-calorie diet that supplies key vitamins and minerals, as well as carbohydrates, proteins, and fats
  • Injections of some vitamins and minerals
  • Vitamin B12, folic acid and increased iron in the diet to treat anemia
  • Medicines to slow down the normal movement of the intestine so food remains in the intestine longer
  • Injections of special growth factors
  • Tube feeding through a vein (parenteral nutrition) if normal feeding is not supplying enough nutrients
  • Small bowel transplantation in some cases

Prognosis (Outlook)

The condition may improve over time if it is due to surgery. Nutrient absorption may slowly get better.

Potential Complications

  • Bacterial overgrowth in the small intestine
  • Nervous system problems caused by a lack of vitamin B12
  • Too much acid in the blood (metabolic acidosis due to diarrhea)
  • Gallstones
  • Kidney stones
  • Malnutrition
  • Weakened bones (osteomalacia)
  • Weight loss

When to Contact a Health Professional

Call your health care provider if you develop symptoms of short bowel syndrome, especially after you have had bowel surgery.


Semrad CE. Approach to the patient with diarrhea and malabsorption. In: Goldman L, Schafer AI, eds. Goldman's Cecil Medicine. 24th ed. Philadelphia, PA: Saunders Elsevier; 2011:chap 142.

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Review Date: 5/15/2014
Reviewed By: Jenifer K. Lehrer, MD, Department of Gastroenterology, Frankford-Torresdale Hospital, Aria Health System, Philadelphia, PA. Review provided by VeriMed Healthcare Network. Also reviewed by David Zieve, MD, MHA, Isla Ogilvie, PhD, and the A.D.A.M. Editorial team.
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Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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Associated drugs

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