Hydromorphone Hydrochloride Injection Shortage

Last Updated: September 15, 2025
Status: Current

Unavailable, Current:

• Dilaudid, Injection, 1 mg/1 mL (Fresenius Kabi USA, LLC)
• Hydromorphone Hydrochloride, Injection, 0.5 mg/0.5 mL NexJect™ Single-dose Syringe Luer Lock (no needle) (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 1 mg/1 mL (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Fresenius Kabi USA, LLC)
• Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Fresenius Kabi USA, LLC)
• Hydromorphone Hydrochloride, Injection, 4 mg/1 mL (Fresenius Kabi USA, LLC)

Limited Availability, Current:

• Hydromorphone Hydrochloride, Injection, 1 mg/1 mL Syringes (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hospira, Inc., a Pfizer Company)

Available, Current:

• Dilaudid, Injection, .2 mg/1 mL (Fresenius Kabi USA, LLC)
• Dilaudid, Injection, 1 mg/1 mL (Fresenius Kabi USA, LLC)
• Dilaudid, Injection, 2 mg/1 mL (Fresenius Kabi USA, LLC)
• Hydromorphone Hydrochloride, Injection, 0.25 mg/ 0.5 mL NexJect™ Single-dose Syringe Luer Lock (no needle) (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 1 mg/1 mL (Fresenius Kabi USA, LLC)
• Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Teva Pharmaceuticals USA, Inc.)
• Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)
• Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 2 mg/1 mL Syringes (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 4 mg/1 mL Syringes (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 50 mg/5 mL (10 mg/mL) (Hospira, Inc., a Pfizer Company)
• Hydromorphone Hydrochloride, Injection, 500 mg/50 mL (10 mg/mL) (Hospira, Inc., a Pfizer Company)

To Be Discontinued:

• Injection, 1 mg/1 mL (Hospira, Inc., a Pfizer Company)

Dilaudid, Injection, 1 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 76045-009-06
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Other
Related Information: Backordered. Next release September 2025. Check wholesalers for inventory.
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 0.5 mg/0.5 mL NexJect™ Single-dose Syringe Luer Lock (no needle) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-4264-01
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Demand increase for the drug
Related Information: Next Delivery: August 2025; Estimated Recovery: December 2025
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 1 mg/1 mL (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1283-37
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Next Delivery: February 2026; Estimated Recovery: March 2026
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-851-10
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Demand increase for the drug
Related Information: Backordered. Next release not available at this time. Check wholesaler for inventory.
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-851-15
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Other
Related Information: Backordered. Next release not available at this time. Check wholesaler for inventory.
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-851-50
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Other
Related Information: Backordered. Next release not available at this time. Check wholesalers for inventory.
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-853-25
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Other
Related Information: Backordered. Next release not available at this time. Check wholesalers for inventory.
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 4 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-854-10
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Other
Related Information: Backordered. Next release not available at this time. Check wholesaler for inventory.
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 1 mg/1 mL Syringes (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1283-31
Availability: Limited Availability
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Limited Supply Available. Next Delivery: September 2025; Estimated Recovery: December 2025
Therapeutic category: Analgesia/Addiction
Change date: January 2, 2025
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1312-36
Availability: Limited Availability
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Limited Supply Available. Next Delivery: January 2026; Estimated Recovery: March 2026
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Dilaudid, Injection, .2 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 76045-121-11
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Check wholesalers for inventory
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 888-386-1300

Dilaudid, Injection, 1 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 76045-009-11
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Dilaudid, Injection, 2 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 76045-010-11
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 0.25 mg/ 0.5 mL NexJect™ Single-dose Syringe Luer Lock (no needle) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1805-01
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 1 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-852-25
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 888-386-1300

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Teva Pharmaceuticals USA, Inc.)

NDC Code: 0703-0110-03
Availability: Available
Status: Current
Date of update: September 15, 2025
Update type: Revised
Reason for shortage: Shortage of an active ingredient
Related Information: Estimated recovery: November 2025
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 800-545-8800

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Teva Pharmaceuticals USA, Inc.)

NDC Code: 0703-0113-03
Availability: Available
Status: Current
Date of update: September 15, 2025
Update type: Revised
Reason for shortage: Shortage of an active ingredient
Related Information: Estimated recovery: December 2025
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 800-545-8800

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Teva Pharmaceuticals USA, Inc.)

NDC Code: 0703-0018-01
Availability: Available
Status: Current
Date of update: September 15, 2025
Update type: Revised
Reason for shortage: Shortage of an active ingredient
Related Information: Estimated recovery: November 2025
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 800-545-8800

Hydromorphone Hydrochloride, Injection, 10 mg/1 mL (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-2634-01
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Change date: January 2, 2025
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-3365-10
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-0121-25
Availability: Available
Status: Current
Date of update: July 23, 2025
Update type: Revised
Related Information: Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Therapeutic category: Analgesia/Addiction
Change date: January 3, 2025
Initial posting date: November 3, 2017
Contact info: 800-631-2174

Hydromorphone Hydrochloride, Injection, 2 mg/1 mL (Hikma Pharmaceuticals USA, Inc.)

NDC Code: 0641-6254-01
Availability: Available
Status: Current
Date of update: July 23, 2025
Update type: Revised
Related Information: Additional lots are scheduled for manufacturing to meet demand. Product will be made available as it is released.
Therapeutic category: Analgesia/Addiction
Initial posting date: November 1, 2017
Contact info: 800-631-2174

Hydromorphone Hydrochloride, Injection, 2 mg/1 mL Syringes (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1312-30
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Change date: January 2, 2025
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 4 mg/1 mL Syringes (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1304-31
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Change date: January 2, 2025
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 50 mg/5 mL (10 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-2634-05
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Change date: January 2, 2025
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Hydromorphone Hydrochloride, Injection, 500 mg/50 mL (10 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-2634-50
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Analgesia/Addiction
Change date: January 2, 2025
Initial posting date: October 31, 2017
Contact info: 844-646-4398

Injection, 1 mg/1 mL (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-2552-01
Status: To Be Discontinued
Date of update: January 13, 2025
Update type: Revised
Related Information: Discontinuation of the manufacture of the drug.
Therapeutic category: Analgesia/Addiction
Change date: January 13, 2025
Date discontinued: January 13, 2025
Initial posting date: November 1, 2017
Contact info: 844-646-4398

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