Bupivacaine Hydrochloride, Epinephrine Bitartrate Injection Shortage

Last Updated: September 2, 2025
Status: Current

Unavailable, Current:

• Bupivacaine Hydrochloride and Epinephrine, Injection, 125 mg/50 mL (2.5 mg/mL) (Hospira, Inc., a Pfizer Company)
• Bupivacaine Hydrochloride and Epinephrine, Injection, 150 mg/30 mL (5 mg/mL) (Hospira, Inc., a Pfizer Company)
• Bupivacaine Hydrochloride And Epinephrine, Injection, 25 mg/10 mL (2.5 mg/mL) (Hospira, Inc., a Pfizer Company)
• Bupivacaine Hydrochloride And Epinephrine, Injection, 250 mg/50 mL (5 mg/mL) (Hospira, Inc., a Pfizer Company)
• Bupivacaine Hydrochloride And Epinephrine, Injection, 50 mg/10 mL (5 mg/mL) (Hospira, Inc., a Pfizer Company)
• Bupivacaine Hydrochloride And Epinephrine, Injection, 75 mg/30 mL (2.5 mg/mL) (Hospira, Inc., a Pfizer Company)
• Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

Limited Availability, Current:

• Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 75 mg/30 mL (2.5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

Available, Current:

• Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 125 mg/50 mL (2.5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)
• Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 150 mg/30 mL (5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)
• Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 25 mg/10 mL (2.5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)
• Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 250 mg/50 mL (5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)
• Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 50 mg/10 mL (5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)
• Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)
• Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)
• Sensorcaine, Injection, 7.5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

Bupivacaine Hydrochloride and Epinephrine, Injection, 125 mg/50 mL (2.5 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-9043-01
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Shortage per Manufacturer: Manufacturing Delay
Therapeutic category: Anesthesia
Change date: December 19, 2024
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Bupivacaine Hydrochloride and Epinephrine, Injection, 150 mg/30 mL (5 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-9045-17
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Shortage per Manufacturer: Manufacturing Delay
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Bupivacaine Hydrochloride And Epinephrine, Injection, 25 mg/10 mL (2.5 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-9042-01
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Shortage per Manufacturer: Manufacturing Delay
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Bupivacaine Hydrochloride And Epinephrine, Injection, 250 mg/50 mL (5 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-9046-01
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Shortage per Manufacturer: Manufacturing Delay
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Bupivacaine Hydrochloride And Epinephrine, Injection, 50 mg/10 mL (5 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-9045-01
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Shortage per Manufacturer: Manufacturing Delay
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Bupivacaine Hydrochloride And Epinephrine, Injection, 75 mg/30 mL (2.5 mg/mL) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-9042-17
Availability: Unavailable
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Shortage per Manufacturer: Manufacturing Delay
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-462-31
Availability: Unavailable
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Reason for shortage: Delay in shipping of the drug
Related Information: Not available at this time.
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 75 mg/30 mL (2.5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1746-30
Availability: Limited Availability
Status: Current
Date of update: August 15, 2025
Update type: Revised
Reason for shortage: Other
Related Information: Limited Supply Available. Next Delivery: August 2025; Estimated Recovery: September 2025
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 125 mg/50 mL (2.5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1752-50
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 150 mg/30 mL (5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1749-29
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 25 mg/10 mL (2.5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1746-10
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 250 mg/50 mL (5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1755-50
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Marcaine With Epinephrine, Injection, Marcaine with Epinephrine 1:200,000 as the bitartrate 50 mg/10 mL (5 mg/mL 1:200,000) (Hospira, Inc., a Pfizer Company)

NDC Code: 0409-1749-10
Availability: Available
Status: Current
Date of update: August 15, 2025
Update type: Reverified
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 844-646-4398

Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-461-57
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesaler for inventory
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-468-17
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Sensorcaine, Injection, 2.5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-468-37
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-463-57
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesaler for inventory
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-462-17
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Sensorcaine, Injection, 5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-462-37
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: Check wholesalers for inventory
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

Sensorcaine, Injection, 7.5 mg/1 mL; .005 mg/1 mL (Fresenius Kabi USA, LLC)

NDC Code: 63323-460-37
Availability: Available
Status: Current
Date of update: September 2, 2025
Update type: Reverified
Related Information: 8 mos expiry available upon request. Check wholesaler for inventory.
Therapeutic category: Anesthesia
Initial posting date: February 20, 2018
Contact info: 888-386-1300

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