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Trimethoprim Drug Interactions

Currently displaying 89 drugs known to have a major interaction with trimethoprim.

See also: The most common drugs checked in combination with this medicine.

Check for interactions

Type in a drug name to check for interactions with trimethoprim.

Medications known to interact with trimethoprim

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    • leucovorin (Wellcovorin)
    • levoleucovorin (Khapzory, Fusilev)
    • lidocaine / potassium chloride
    • lisinopril (Zestril, Prinivil, Qbrelis)
    • losartan (Cozaar)
    • lvp solution with potassium (Potassium Chloride in Sodium Chloride, Dextrose 10% and Electrolyte No 48, Isolyte E, Isolyte P and 5% Dextrose, Plasma-Lyte 56 and 5% Dextrose, Dextrose 5% And Electrolyte No. 48 Injection, Plasma-Lyte 56, Normosol-M and 5% Dextrose, Isolyte M and 5% Dextrose, Ionosol MB and 5% Dextrose, Ionosol T and 5% Dextrose, Isolyte H and 5 % Dextrose, Ionosol B and 5% Dextrose, Isolyte R and 5% Dextrose, Plasma-Lyte and 5% Dextrose, Travert 10% and Electrolyte No2, Travert 5% and Electrolyte No2)
    M
    • methotrexate (Rasuvo, Methotrexate LPF Sodium, Trexall, Otrexup, Rheumatrex Dose Pack, Xatmep, Folex PFS)
    • moexipril (Univasc)
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    Trimethoprim alcohol/food interactions

    There is 1 alcohol/food interaction with trimethoprim

    Trimethoprim disease interactions

    There are 3 disease interactions with trimethoprim which include:

    Drug Interaction Classification

    These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No interaction information available.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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