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Drug Interactions between telbivudine and tenofovir alafenamide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

tenofovir telbivudine

Applies to: tenofovir alafenamide and telbivudine

Tenofovir can affect kidney function and may increase the blood levels and effects of telbivudine when used together. You may be more likely to develop serious side effects of telbivudine including liver, muscle, and nerve problems. Contact your doctor if you develop skin rash or itching; loss of appetite; abdominal pain; nausea; vomiting; dark colored urine; yellowing of the skin or eyes; unexplained muscle aches, pain, tenderness, or weakness; difficulty walking; or numbness, burning or tingling in your hands and feet. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience extreme tiredness or weakness, dizziness, lightheadedness, muscle pain, difficulty breathing, stomach pain, nausea, vomiting, and/or a fast or irregular heart beat, as these may be signs and symptoms of a serious medical condition known as lactic acidosis that can sometimes occur during treatment with medications like telbivudine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Minor

tenofovir food

Applies to: tenofovir alafenamide

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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