Drug interactions between Suboxone and Talwin
Interactions between your drugs
pentazocine ↔ buprenorphine
Applies to:Talwin (pentazocine) and Suboxone (buprenorphine/naloxone)
Using pentazocine together with other medications that cause central nervous system depression such as buprenorphine can lead to serious side effects including respiratory distress, coma, and even death. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
naloxone ↔ pentazocine
Applies to:Suboxone (buprenorphine/naloxone) and Talwin (pentazocine)
The following interaction applies only if you are taking naloxone in an injectable formulation: Using pentazocine together with naloxone can reverse the effects of pentazocine. If you are a physically dependent patient you may experience withdrawal symptoms. This can cause nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or special tests to safely take both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug Interaction Classification
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Do not stop taking any medications without consulting your healthcare provider.