Drug Interactions between Suboxone and Talwin
This report displays the potential drug interactions for the following 2 drugs:
- Suboxone (buprenorphine/naloxone)
- Talwin (pentazocine)
Interactions between your drugs
Applies to: Talwin (pentazocine) and Suboxone (buprenorphine / naloxone)
Using pentazocine together with other medications that cause central nervous system depression such as buprenorphine can lead to serious side effects including respiratory distress, coma, and even death. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Do not drink alcohol or self-medicate with these medications without your doctor's approval, and do not exceed the doses or frequency and duration of use prescribed by your doctor. Also, you should avoid driving or operating hazardous machinery until you know how these medications affect you. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Applies to: Suboxone (buprenorphine / naloxone) and Talwin (pentazocine)
The following interaction applies only if you are using naloxone in an injectable formulation:
naloxone can reverse the effects of pentazocine. If you are a physically dependent patient you may experience withdrawal symptoms. This can cause nausea, vomiting, diarrhea, aches, fever, runny nose, sneezing, nervousness, irritability, shivering, and abdominal cramps. Talk to your doctor if you have any questions or concerns. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Talwin (pentazocine)
Smoking tobacco may reduce the blood levels and effects of pentazocine. Contact your doctor if pentazocine is not adequately controlling your symptoms.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No interaction information available.|
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.