Drug Interactions between sotorasib and Vimovo
This report displays the potential drug interactions for the following 2 drugs:
- sotorasib
- Vimovo (esomeprazole/naproxen)
Interactions between your drugs
esomeprazole sotorasib
Applies to: Vimovo (esomeprazole / naproxen) and sotorasib
By reducing the acidity level in the stomach, medications like esomeprazole may interfere with the absorption of sotorasib into the bloodstream and reduce its effectiveness. It is generally best to avoid using these medications together when possible. Some prescription and over-the-counter medications may also contain antacids or other agents that can neutralize acid. You should check the ingredients of all medications you take to see if they may contain antacids. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
naproxen esomeprazole
Applies to: Vimovo (esomeprazole / naproxen) and Vimovo (esomeprazole / naproxen)
Talk to your doctor before using naproxen together with esomeprazole. Using these medications together may affect the enteric coating of naproxen, causing the medication to be released too early in the body. This can make naproxen less effective. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
esomeprazole food
Applies to: Vimovo (esomeprazole / naproxen)
Food may interfere with the absorption of esomeprazole. Esomeprazole should be taken at least one hour before meals and at the same time every day. When esomeprazole is given to patients receiving continuous enteral nutrition (tube feedings), the tube feeding should be interrupted for at least 1 hour before and 1 hour after the dose of esomeprazole. This will make it easier for your body to absorb the medication. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
naproxen food
Applies to: Vimovo (esomeprazole / naproxen)
Ask your doctor before using naproxen together with ethanol. Do not drink alcohol while taking naproxen. Alcohol can increase your risk of stomach bleeding caused by naproxen. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
sotorasib food
Applies to: sotorasib
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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