Skip to Content
Learn about Adcetris a treatment of Hodgkin Lymphoma

Drug interactions between ribociclib and trametinib

Results for the following 2 drugs:
ribociclib
trametinib

Interactions between your drugs

There were no interactions found in our database between ribociclib and trametinib - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

ribociclib

A total of 781 drugs (3084 brand and generic names) are known to interact with ribociclib.

trametinib

A total of 7 drugs (14 brand and generic names) are known to interact with trametinib.

Drug and food interactions

Moderate

trametinib food

Applies to: trametinib

Food may delay and reduce the absorption of trametinib, which may lead to lower blood levels of the medication and possibly reduced effectiveness. You should take trametinib at least 1 hour before or 2 hours after a meal.

Switch to professional interaction data

Moderate

ribociclib food

Applies to: ribociclib

Patients should not consume pomegranates, pomegranate juice, grapefruit, or grapefruit juice during treatment with ribociclib unless directed otherwise by your doctor. Pomegranate juice or grapefruit juice can increase the blood levels of ribociclib. You may be more likely to experience side effects such as nausea; vomiting; diarrhea; loss of appetite; abdominal pain; mouth sores; hair loss; weakness; and impaired bone marrow function resulting in low numbers of different types of blood cells, which can increase the risk of anemia, bleeding problems, and infections. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Hide