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Four-Way Nasal Spray (oxymetazoline nasal) Drug Interactions

A total of 75 drugs are known to interact with Four-Way Nasal Spray (oxymetazoline nasal).

  • 9 major drug interactions
  • 66 moderate drug interactions

Show all medications in the database that may interact with Four-Way Nasal Spray (oxymetazoline nasal).

Check for interactions with Four-Way Nasal Spray (oxymetazoline nasal)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Four-Way Nasal Spray (oxymetazoline nasal)

  • 4 Way Saline (sodium chloride nasal)
  • albuterol (Ventolin, ProAir HFA, Ventolin HFA, Proventil, Proventil HFA, ProAir RespiClick, Respirol, AccuNeb, Vospire ER, Airet, Volmax, ProAir Digihaler)
  • doxycycline (Vibramycin, Doxy 100, Oracea, Monodox, Adoxa, Doryx, Acticlate, Vibra-Tabs, Targadox, Doxy 200, Doxy-D, Oraxyl, Alodox, Morgidox, Adoxa Pak, Avidoxy, Uracil, Periostat, Doryx MPC, Doxy-Caps, Adoxa TT, Adoxa CK, Ocudox, LymePak, Mondoxyne NL, NicAzel Doxy, Doxy-Lemmon)
  • Fish Oil (omega-3 polyunsaturated fatty acids)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • lorazepam (Ativan, Lorazepam Intensol)
  • losartan (Cozaar)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • ondansetron (Zofran, Zofran ODT, Zuplenz)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, Oxydose, RoxyBond, Dazidox, Oxecta, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • pantoprazole (Protonix, Protonix IV)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Provigil (modafinil)
  • testosterone (AndroGel, Depo-Testosterone, Androderm, Testim, Axiron, Testopel, Fortesta, Aveed, Delatestryl, Xyosted, Natesto, Vogelxo, Testoderm, Testopel Pellets, Striant, Testamone-100, Everone, FIRST-Testosterone MC, FIRST-Testosterone, Testro AQ, Testolin, Depotest, Virilon IM, Delatest, Andro LA 200, Andro-Cyp 100, Andro-Cyp 200, Depandro 100, Duratest, Durathate 200, Histerone, Meditest, Testro, Testro-LA, Testo-100)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Tylenol (acetaminophen)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zyrtec (cetirizine)

Four-Way Nasal Spray (oxymetazoline nasal) disease interactions

There are 3 disease interactions with Four-Way Nasal Spray (oxymetazoline nasal) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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