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Afrin Sinus (oxymetazoline nasal) Drug Interactions

A total of 75 drugs are known to interact with Afrin Sinus (oxymetazoline nasal).

  • 9 major drug interactions
  • 66 moderate drug interactions

Show all medications in the database that may interact with Afrin Sinus (oxymetazoline nasal).

Check for interactions with Afrin Sinus (oxymetazoline nasal)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Afrin Sinus (oxymetazoline nasal)

  • Advil (ibuprofen)
  • Afrin (oxymetazoline nasal)
  • albuterol (ProAir HFA, Ventolin, Ventolin HFA, Proventil, Proventil HFA, ProAir RespiClick, Respirol, AccuNeb, Volmax, Airet, Vospire ER)
  • Aspirin Low Strength (aspirin)
  • atorvastatin (Lipitor)
  • azithromycin (Zithromax, Azithromycin Dose Pack, Z-Pak, Zmax)
  • Benadryl (diphenhydramine)
  • cetirizine (Zyrtec, Aller-Tec, Zyrtec Hives, All Day Allergy, Children's Allergy Relief, PediaCare Children's 24-Hour Allergy, All Day Allergy Children's, Equate Allergy Relief, Children's Zyrtec, Alleroff, Aller-Tec Children's)
  • diazepam (Valium, Diastat, Diazepam Intensol, Diastat AcuDial, Zetran, Diastat Pediatric, Dizac, Valrelease)
  • Flonase (fluticasone nasal)
  • hydrocodone (Hysingla ER, Zohydro ER, Vantrela ER)
  • ibuprofen (Advil, Motrin, IBU, Proprinal, Advil Liqui-Gels, Motrin IB, IBU-200, Nuprin, Children's Motrin, Motrin Migraine Pain, Advil Migraine, Caldolor, Ibuprofen PMR, Advil Children's, Addaprin, NeoProfen, Advil Infant's Concentrated Drops, A-G Profen, Motrin Childrens, Childrens Ibuprofen Berry, Ibu-6, Ibu-8, Motrin Infant Drops, Ibu-Tab, Rufen, Genpril, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • levofloxacin (Levaquin, Levaquin Leva-Pak)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • lorazepam (Ativan, Lorazepam Intensol)
  • meclizine (Antivert, Dramamine Less Drowsy, Bonine, Meclicot, Travel Sickness, Dramamine All Day Less Drowsy, Travel-Ease, Antrizine, Medivert, Dramamine II, D-Vert, Driminate II, Ru-Vert-M, Meni-D, Help I'm Nauseous, Motion-Time, Sea-Calm, Verticalm)
  • melatonin (Melatonin Time Release, Bio-Melatonin, SGard, Health Aid Melatonin, VesPro Melatonin)
  • prednisone (Deltasone, Rayos, Sterapred DS, Sterapred, Prednicot, Meticorten, Liquid Pred, Orasone, Prednicen-M)
  • simvastatin (Zocor, FloLipid)
  • tamsulosin (Flomax)
  • Tylenol (acetaminophen)
  • Vitamin D3 (cholecalciferol)

Afrin Sinus (oxymetazoline nasal) disease interactions

There are 3 disease interactions with Afrin Sinus (oxymetazoline nasal) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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