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OxyIR (oxycodone) Drug Interactions

A total of 951 drugs are known to interact with OxyIR (oxycodone).

  • 340 major drug interactions
  • 609 moderate drug interactions
  • 2 minor drug interactions

Show all medications in the database that may interact with OxyIR (oxycodone).

Check for interactions with OxyIR (oxycodone)

Type in a drug name and select a drug from the list.

Common medications checked in combination with OxyIR (oxycodone)

  • Ambien (zolpidem)
  • Ativan (lorazepam)
  • baclofen (Lioresal, Gablofen, Kemstro, Lioresal Intrathecal)
  • clonazepam (Klonopin, Klonopin Wafer)
  • Cymbalta (duloxetine)
  • Fentanyl Transdermal System (fentanyl)
  • Flexeril (cyclobenzaprine)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • Lyrica (pregabalin)
  • metformin (Glucophage, Glucophage XR, Glumetza, Riomet, Fortamet)
  • morphine (MS Contin, Morphine Sulfate ER, Roxanol, Morphine Sulfate IR, Kadian, MSIR, MorphaBond ER, Duramorph, Statex, Avinza, Arymo ER, Morphine Sulfate SR, Morphine LP Epidural, Oramorph SR, Astramorph PF, Mitigo, Morphine Rapi-Ject, RMS, Infumorph, Duramorph PF, OMS, Roxanol 100, Rescudose, MS/S, Roxanol-T, Doloral, Doloral Sirop, M-Eslon, Morphitec, M O S)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, Oxydose, RoxyBond, Dazidox, Oxecta, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • OxyContin (oxycodone)
  • Percocet (acetaminophen / oxycodone)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • tizanidine (Zanaflex)
  • trazodone (Desyrel, Oleptro, Desyrel Dividose)
  • Valium (diazepam)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)
  • Zoloft (sertraline)

OxyIR (oxycodone) alcohol/food interactions

There is 1 alcohol/food interaction with OxyIR (oxycodone)

OxyIR (oxycodone) disease interactions

There are 17 disease interactions with OxyIR (oxycodone) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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