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Endocodone (oxycodone) Drug Interactions

A total of 951 drugs are known to interact with Endocodone (oxycodone).

  • 340 major drug interactions
  • 609 moderate drug interactions
  • 2 minor drug interactions

Show all medications in the database that may interact with Endocodone (oxycodone).

Check for interactions with Endocodone (oxycodone)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Endocodone (oxycodone)

  • Amoxil (amoxicillin)
  • baclofen (Lioresal, Gablofen, Kemstro, Lioresal Intrathecal)
  • Cymbalta (duloxetine)
  • diazepam (Valium, Diastat, Diazepam Intensol, Diastat AcuDial, Zetran, Diastat Pediatric, Dizac, Valrelease)
  • doxylamine (Sleep Aid, Unisom SleepTabs, Equate Sleep Aid, Fast Sleep, Nighttime Sleepaid, Care One Sleep Aid, Doxytex, Aldex AN Chewable, Aldex AN, Nytol Maximum Strength, Equaline Sleep Aid, Medi-Sleep)
  • Eutroxsig (levothyroxine)
  • Fentanyl Transdermal System (fentanyl)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Keflex (cephalexin)
  • loperamide (Imodium, Imodium A-D, Anti-Diarrheal, Imotil, Kaopectate II, Neo-Diaral, Pepto Diarrhea Control, Kao-Paverin, Diar-Aid, Diamode, Up and Up Anti-Diarrheal Solution, Kaopectate 1-D, A-D Anti-Diarrheal)
  • Metamucil (psyllium)
  • naloxone (Evzio, Narcan Nasal Spray, Narcan Injection)
  • Nexium (esomeprazole)
  • pantoprazole (Protonix, Protonix IV)
  • prednisolone (Prelone, Orapred, Millipred, Orapred ODT, PediaPred, Predalone 50, Flo-Pred, Veripred 20, AsmalPred Plus, Delta-Cortef, Hydeltra-TBA, Hydeltrasol, Key-Pred, Cotolone, Predicort-50, Predacort 50, Predate-50, Predaject-50, Pred-Ject-50, Key-Pred SP, Medicort, Predicort RP, Pri-Cortin 50, Predcor, Bubbli-Pred, Millipred DP)
  • sertraline (Zoloft)
  • Targiniq ER (naloxone / oxycodone)
  • temazepam (Restoril)
  • Valium (diazepam)
  • Vitamin D3 (cholecalciferol)

Endocodone (oxycodone) alcohol/food interactions

There is 1 alcohol/food interaction with Endocodone (oxycodone)

Endocodone (oxycodone) disease interactions

There are 17 disease interactions with Endocodone (oxycodone) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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