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Drug interactions between Otrexup and Rasuvo

Results for the following 2 drugs:
Otrexup (methotrexate)
Rasuvo (methotrexate)

Interactions between your drugs

There were no interactions found in our database between Otrexup and Rasuvo - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.


A total of 862 drugs are known to interact with Otrexup.


A total of 862 drugs are known to interact with Rasuvo.

Drug and food interactions


methotrexate food

Applies to: Otrexup (methotrexate) and Rasuvo (methotrexate)

Caffeine may reduce the effectiveness of methotrexate in the treatment of arthritis. If you are receiving methotrexate for arthritis, you may want to limit your intake of caffeine-containing foods and medications. Check with your doctor or pharmacist if you have concerns or are uncertain what products may contain caffeine.

Switch to professional interaction data

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.