Drug interactions between omeprazole and Vosevi
Interactions between your drugs
omeprazole ↔ velpatasvir
Applies to:omeprazole and Vosevi (sofosbuvir/velpatasvir/voxilaprevir)
Depending on the dose, omeprazole may interfere with the absorption of velpatasvir and reduce its effectiveness. Talk to your doctor or pharmacist if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment of omeprazole to safely use both medications. You should take velpatasvir with food and at least 4 hours before the dose of omeprazole. Contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Vosevi (sofosbuvir / velpatasvir / voxilaprevir)
Food may help the absorption of voxilaprevir. You should take this medication with food as directed.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.