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Drug Interactions between Mykrox and Visudyne

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

metOLazone verteporfin

Applies to: Mykrox (metolazone) and Visudyne (verteporfin)

Using verteporfin together with metOLazone may cause an increase in photosensitivity reactions, which could cause your skin to burn when exposed to light. Check with your doctor to see if you should temporarily withhold any of your medications before and after treatment with verteporfin. You should avoid exposure of skin or eyes to sunlight or bright indoor lights (examination lamps, operating room lamps, tanning beds, lights at close proximity) for 5 days after treatment with verteporfin. If you must go outdoors in the daylight during this 5-day time frame it is important to protect your skin and eyes by wearing protective clothing and dark sunglasses, even if you cannot see the sun (e.G., cloudy day). Exposing your skin to normal indoor lighting is helpful as it will help your body get rid of verteporfin more quickly, so you do not need to stay inside in the dark. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

metOLazone food

Applies to: Mykrox (metolazone)

MetOLazone and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.