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Depo-Medrol (methylprednisolone) Drug Interactions

A total of 773 drugs are known to interact with Depo-Medrol (methylprednisolone).

  • 94 major drug interactions
  • 599 moderate drug interactions
  • 80 minor drug interactions

Show all medications in the database that may interact with Depo-Medrol (methylprednisolone).

Check for interactions with Depo-Medrol (methylprednisolone)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Depo-Medrol (methylprednisolone)

  • cetirizine (Zyrtec, Aller-Tec, Zyrtec Hives, All Day Allergy Children's, Equate Allergy Relief, PediaCare Children's 24-Hour Allergy, All Day Allergy, Children's Allergy Relief, Children's Zyrtec, Alleroff, Aller-Tec Children's)
  • cyclobenzaprine (Flexeril, Amrix, Fexmid, Comfort Pac with Cyclobenzaprine)
  • Cymbalta (duloxetine)
  • dexamethasone (Decadron, Dexamethasone Intensol, Decadron Phosphate, Injectable, Dexasone, Hexadrol, Dexacort Phosphate in Respihaler, Zonacort, TaperDex, Dexacen-4, ZoDex, LoCort, Adrenocot LA, Dalalone, Dalalone DP, Dalalone LA, Decaject, Decaject LA, Zema Pak, Baycadron, Decadron-LA, Solurex LA, Solurex, Adrenocot, De-Sone LA, Dexacort-LA, Dexasone LA, Dexone, Dexone LA, Primethasone, Dexacorten, Medidex, Medidex LA, Dexpak Taperpak)
  • Flexeril (cyclobenzaprine)
  • folic acid (Folvite, FA-8, Folacin-800, FaLessa)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • ibuprofen (Advil, Motrin, IBU, Advil Liqui-Gels, Proprinal, Motrin IB, Children's Motrin, IBU-200, Advil Migraine, Ibu-8, Motrin Childrens, Nuprin, Motrin Migraine Pain, Ibuprofen PMR, NeoProfen, Caldolor, Advil Children's, Addaprin, Motrin Infant Drops, Advil Infant's Concentrated Drops, Rufen, Genpril, A-G Profen, Ibu-Tab, Haltran, Menadol, Midol IB, Saleto-200, Q-Profen, Saleto-400, Saleto-600, Saleto-800, Advil Junior Strength, Midol Maximum Strength Cramp Formula, Actiprofen, Childrens Ibuprofen Berry, PediaCare Infants' IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-4, PediaCare Children's IB Ibuprofen Pain Reliever/Fever Reducer, Ibu-6, Motrin Junior Strength, Help I Have An Aching Body, Children's ElixSure IB, Cap-Profen, Motrin Pediatric, Advil Film-Coated)
  • Lexapro (escitalopram)
  • lidocaine (DentiPatch, Xylocaine-MPF, Lidoject 1, Xylocaine HCl, Xylocaine Dental Cartridges, Lidoject 2, Xylocaine Duo-Trach Kit, Xylocaine HCl For Spinal, L-Caine, Dilocaine, Nervocaine, Truxacaine, UAD Caine, Anestacaine)
  • Lipitor (atorvastatin)
  • Lyrica (pregabalin)
  • Marcaine (bupivacaine)
  • meloxicam (Mobic, Vivlodex, Qmiiz ODT)
  • Nexium (esomeprazole)
  • Norco (acetaminophen / hydrocodone)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • pantoprazole (Protonix, Protonix IV)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Solu-Medrol (methylprednisolone)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Vitamin B12 (cyanocobalamin)
  • Vitamin D3 (cholecalciferol)
  • Xanax (alprazolam)

Depo-Medrol (methylprednisolone) alcohol/food interactions

There are 3 alcohol/food interactions with Depo-Medrol (methylprednisolone)

Depo-Medrol (methylprednisolone) disease interactions

There are 24 disease interactions with Depo-Medrol (methylprednisolone) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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