Drug Interactions between Magnaprin and sparsentan
This report displays the potential drug interactions for the following 2 drugs:
- Magnaprin (aluminum hydroxide/aspirin/calcium carbonate/magnesium hydroxide)
- sparsentan
Interactions between your drugs
aspirin calcium carbonate
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Using calcium carbonate together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin aluminum hydroxide
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Using aluminum hydroxide together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin magnesium hydroxide
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Using magnesium hydroxide together with aspirin may decrease the effects of aspirin. Contact your doctor if your condition changes. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin sparsentan
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and sparsentan
Talk to your doctor before using sparsentan together with aspirin. Combining these medications may reduce the effects of sparsentan in lowering blood pressure. In addition, these medications may affect your kidney function, especially when they are used together frequently or chronically. You are more likely to develop impaired kidney function during treatment with these medications if you are also using a diuretic ("water pill") or if you are elderly or have preexisting kidney disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
calcium carbonate sparsentan
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and sparsentan
By reducing the acidity level in the stomach, medications like calcium carbonate may interfere with the absorption of sparsentan into the bloodstream and reduce its effectiveness. It is generally best to avoid using these medications together when possible. However, if you have no other alternatives for treatment, it is recommended that you take calcium carbonate 2 hours before or 2 hours after sparsentan to help minimize the impact of the interaction. Some prescription and over-the-counter medications may also contain antacids or other agents that can neutralize acid. You should check the ingredients of all medications you take to see if they may contain antacids. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aluminum hydroxide sparsentan
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and sparsentan
By reducing the acidity level in the stomach, medications like aluminum hydroxide may interfere with the absorption of sparsentan into the bloodstream and reduce its effectiveness. It is generally best to avoid using these medications together when possible. However, if you have no other alternatives for treatment, it is recommended that you take aluminum hydroxide 2 hours before or 2 hours after sparsentan to help minimize the impact of the interaction. Some prescription and over-the-counter medications may also contain antacids or other agents that can neutralize acid. You should check the ingredients of all medications you take to see if they may contain antacids. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
magnesium hydroxide sparsentan
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide) and sparsentan
By reducing the acidity level in the stomach, medications like magnesium hydroxide may interfere with the absorption of sparsentan into the bloodstream and reduce its effectiveness. It is generally best to avoid using these medications together when possible. However, if you have no other alternatives for treatment, it is recommended that you take magnesium hydroxide 2 hours before or 2 hours after sparsentan to help minimize the impact of the interaction. Some prescription and over-the-counter medications may also contain antacids or other agents that can neutralize acid. You should check the ingredients of all medications you take to see if they may contain antacids. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
aluminum hydroxide food
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Citrate, or citric acid, can increase the absorption of aluminum hydroxide. This may lead to elevated blood levels of aluminum, particularly in individuals with reduced kidney function, since aluminum is primarily eliminated by the kidneys. Excess aluminum may deposit and cause problems in various tissues including bone, brain, heart, liver, muscles, and spleen. Over time, weak bones, bone pain, fractures, skeletal deformity, brain disorders, and anemia may develop. Talk to your doctor before using aluminum hydroxide if you have kidney impairment or are on hemodialysis. You should avoid or limit the consumption of citrate-containing foods and beverages (e.G., soft drinks, citrus fruits, fruit juices) during treatment with aluminum hydroxide. Be aware that some effervescent and dispersible drug formulations may also contain citrate and should be restricted as well. Even if you do not have kidney problems, it may be best to separate the dosing of aluminum hydroxide and citrate-containing products by 2 to 3 hours. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
When aluminum hydroxide is taken during enteral nutrition therapy (tube feeding), the tube may get clogged. Therefore, aluminum hydroxide should not be mixed with or given after high-protein tube feedings. The dose should be separated from the feeding by as much as possible, and the tube should be thoroughly flushed before administration of the dose.
sparsentan food
Applies to: sparsentan
If you are taking sparsentan you should avoid potassium-containing salt substitutes or over-the-counter potassium supplements without first talking to your doctor. This can cause high levels of potassium in your blood. High levels of potassium can cause weakness, irregular heartbeat, confusion, tingling of the extremities, or feelings of heaviness in the legs. Call your doctor at once if you have any of these symptoms.
Consumption of grapefruit, grapefruit juice, and supplements that contain grapefruit should be avoided during treatment with sparsentan as they may increase the blood levels of sparsentan. This may increase the risk of side effects such as hepatotoxicity, acute kidney injury, hyperkalemia, edema, and hypotension.
Swallow sparsentan whole with water before your morning or evening meal. Take your dose with the same meal each day. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
calcium carbonate food
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Calcium absorption may be increased by taking it with food. However, foods high in oxalic acid (spinach or rhubarb), or phytic acid (bran and whole grains) may decrease calcium absorption. Calcium may be taken with food to increase absorption. Consider spacing calcium administration for at least 2 hours before or after consuming foods high in oxalic acid or phytic acid. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin food
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Ask your doctor before using aspirin together with ethanol (alcohol). Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
aspirin food
Applies to: Magnaprin (aluminum hydroxide / aspirin / calcium carbonate / magnesium hydroxide)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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