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Drug interactions between Lomedia 24 Fe and Minastrin 24 Fe

Results for the following 2 drugs:
Lomedia 24 Fe (ethinyl estradiol/norethindrone)
Minastrin 24 Fe (ethinyl estradiol/norethindrone)

Interactions between your drugs

There were no interactions found in our database between Lomedia 24 Fe and Minastrin 24 Fe - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

Lomedia 24 Fe

A total of 605 drugs are known to interact with Lomedia 24 Fe.

Minastrin 24 Fe

A total of 605 drugs are known to interact with Minastrin 24 Fe.

Drug and food interactions

Moderate

norethindrone food

Applies to: Lomedia 24 Fe (ethinyl estradiol / norethindrone) and Minastrin 24 Fe (ethinyl estradiol / norethindrone)

Consumer information for this interaction is not currently available.

MONITOR: Grapefruit juice may increase the plasma concentrations of orally administered drugs that are substrates of the CYP450 3A4 isoenzyme. The proposed mechanism is inhibition of CYP450 3A4-mediated first-pass metabolism in the gut wall by certain compounds present in grapefruit. Because grapefruit juice inhibits primarily intestinal rather than hepatic CYP450 3A4, the magnitude of interaction is greatest for those drugs that undergo significant presystemic metabolism by CYP450 3A4 (i.e., drugs with low oral bioavailability). In general, the effect of grapefruit juice is concentration-, dose- and preparation-dependent, and can vary widely among brands. Certain preparations of grapefruit juice (e.g., high dose, double strength) have sometimes demonstrated potent inhibition of CYP450 3A4, while other preparations (e.g., low dose, single strength) have typically demonstrated moderate inhibition. Pharmacokinetic interactions involving grapefruit juice are also subject to a high degree of interpatient variability, thus the extent to which a given patient may be affected is difficult to predict.

MANAGEMENT: Patients who regularly consume grapefruit or grapefruit juice should be monitored for adverse effects and altered plasma concentrations of drugs that undergo significant presystemic metabolism by CYP450 3A4. Grapefruit and grapefruit juice should be avoided if an interaction is suspected. Orange juice is not expected to interact with these drugs.

Minor

ethinyl estradiol food

Applies to: Lomedia 24 Fe (ethinyl estradiol / norethindrone) and Minastrin 24 Fe (ethinyl estradiol / norethindrone)

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.

Duplication

Estrogens

Therapeutic duplication

The recommended maximum number of medicines in the 'estrogens' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'estrogens' category:

  • Lomedia 24 Fe (ethinyl estradiol/norethindrone)
  • Minastrin 24 Fe (ethinyl estradiol/norethindrone)

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Duplication

Progestins

Therapeutic duplication

The recommended maximum number of medicines in the 'progestins' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'progestins' category:

  • Lomedia 24 Fe (ethinyl estradiol/norethindrone)
  • Minastrin 24 Fe (ethinyl estradiol/norethindrone)

Note: The benefits of taking this combination of medicines may outweigh any risks associated with therapeutic duplication. This information does not take the place of talking to your doctor. Always check with your healthcare provider to determine if any adjustments to your medications are needed.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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