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Zyvox (linezolid) Drug Interactions

A total of 1004 drugs are known to interact with Zyvox (linezolid).

  • 433 major drug interactions
  • 568 moderate drug interactions
  • 3 minor drug interactions

Show all medications in the database that may interact with Zyvox (linezolid).

Check for interactions with Zyvox (linezolid)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Zyvox (linezolid)

  • Adderall (amphetamine / dextroamphetamine)
  • albuterol (Ventolin, ProAir HFA, Ventolin HFA, Proventil, Proventil HFA, ProAir RespiClick, Respirol, AccuNeb, Vospire ER, Airet, Volmax, ProAir Digihaler)
  • aspirin (Aspir 81, Ecotrin, Acetylsalicylic Acid, Aspirin Low Strength, Bayer Aspirin, Aspir-Low, Ascriptin, Ecotrin Adult Low Strength, Bufferin, Aspiritab, Arthritis Pain, Fasprin, Halfprin, Easprin, Durlaza, Aspirtab, St. Joseph 81 mg Chewable Aspirin, Aspergum, Low Dose ASA, Buffered Aspirin, Ecotrin Maximum Strength, Ascriptin Enteric, Acuprin 81, St. Joseph 81 mg Aspirin Enteric Safety-Coated, Aspirin Lite Coat, Bayer Aspirin Regimen, Aspi-Cor, Empirin, Bayer Children's Aspirin, Bufferin Extra Strength, St. Joseph Aspirin, Bayer Women's Aspirin With Calcium, Miniprin, Migralex, Ascriptin Maximum Strength, Arthritis Foundation Pain Reliever, Bayer Aspirin with Heart Advantage, Bufferin Low Dose, Medi-Seltzer, Sloprin, ZORprin, Bayer Aspirin Extra Strength Plus, Buffex, Entercote, Extra Strength Bayer, Genacote, Gennin-FC, Genprin, Litecoat Aspirin, Minitabs, Tri-Buffered Aspirin, Entaprin, Bufferin Arthritis Strength, Therapy Bayer, Stanback Analgesic, Norwich Aspirin, Ecpirin, Zero-Order Release, YSP Aspirin, Heartline, Bayer Advanced Aspirin, Buffasal)
  • Benadryl (diphenhydramine)
  • Cipro (ciprofloxacin)
  • clindamycin (Cleocin, Cleocin Pediatric, Cleocin HCl, Cleocin Phosphate, Cleocin Phosphate ADD-Vantage)
  • Coumadin (warfarin)
  • Cymbalta (duloxetine)
  • Dextrose (glucose)
  • fentanyl (Duragesic, Fentanyl Transdermal System, Actiq, Abstral, Subsys, Sublimaze, Lazanda, Fentora, Ionsys, Onsolis)
  • furosemide (Lasix, Diaqua-2, Lo-Aqua)
  • gabapentin (Neurontin, Gralise, Gabarone, Fanatrex)
  • Lasix (furosemide)
  • Levaquin (levofloxacin)
  • lisinopril (Zestril, Prinivil, Qbrelis)
  • metoprolol (Metoprolol Tartrate, Metoprolol Succinate ER, Toprol-XL, Lopressor, Kapspargo Sprinkle)
  • omeprazole (Prilosec, Prilosec OTC, Zegerid (Original Formulation), Omesec)
  • oxycodone (OxyContin, Roxicodone, Xtampza ER, OxyIR, Oxaydo, Percolone, Oxyfast, Oxydose, RoxyBond, Dazidox, Oxecta, M-Oxy, ETH-Oxydose, Endocodone, Roxicodone Intensol)
  • potassium chloride (Klor-Con, KCl, K-Dur, Klor-Con M20, Micro-K, K-Tab, Klor-Con M10, K-Dur 20, Kay Ciel, Klor-Con 10, K-Lor, Klor-Con Sprinkle, Kaon-CI, Slow-K, Klor-Con 8, Klotrix, Kal Potassium 99, Cena K, K-8, K-Dur 10, Epiklor, Kaochlor, K-Norm, Micro-K 10, Kaochlor S-F, Kaon-CL 20%, K-Sol, K + Potassium, Klor-Con/25, K-10, Glu-K, Kaon-CL 10, Kato, Ed K+10, PC-10, Ten-K, Klor-Con M15, K-Vescent (Potassium Chloride), K+Care, Klorvess, Rum-K, Gen-K)
  • prednisone (Deltasone, Rayos, Sterapred, Sterapred DS, Prednicot, Meticorten, Orasone, Liquid Pred, Prednicen-M)
  • Protonix (pantoprazole)
  • Synthroid (levothyroxine)
  • tramadol (Ultram, Tramadol Hydrochloride ER, Tramal, Ultram ER, Larapam SR, Tramedo, Ryzolt, GenRx Tramadol, ConZip, Zydol, Tramal SR, Tramahexal, Zamadol, Tramahexal SR, Zydol XL, Rybix ODT, Ultram ODT)
  • Tylenol (acetaminophen)
  • vancomycin (Vancocin, Firvanq, Vancocin HCl, Lyphocin, Vancocin HCl Pulvules)
  • Vitamin D3 (cholecalciferol)
  • Zofran (ondansetron)
  • Zoloft (sertraline)
  • Zosyn (piperacillin / tazobactam)

Zyvox (linezolid) alcohol/food interactions

There are 2 alcohol/food interactions with Zyvox (linezolid)

Zyvox (linezolid) disease interactions

There are 12 disease interactions with Zyvox (linezolid) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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