Drug interactions between letrozole and palbociclib
Interactions between your drugs
There were no interactions found in our database between letrozole and palbociclib - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.
- Letrozole is in the following drug classes: aromatase inhibitors, hormones/antineoplastics.
- Letrozole is used to treat the following conditions:
- Palbociclib is a member of the drug class CDK 4/6 inhibitors.
- Palbociclib is used to treat the following conditions:
Drug and food interactions
Applies to: palbociclib
Palbociclib should be taken with food to help with its absorption. Do not consume grapefruit or grapefruit juice during treatment with palbociclib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of palbociclib. You may be more likely to experience side effects such as nausea; vomiting; diarrhea; loss of appetite; mouth sores; hair loss; weakness; pain, numbness, or tingling in the hands and feet; and impaired bone marrow function resulting in low numbers of different types of blood cells, which can increase the risk of anemia, bleeding problems, and infections. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.