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Drug Interactions between Lanoxicaps and Yosprala

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

aspirin digoxin

Applies to: Yosprala (aspirin / omeprazole) and Lanoxicaps (digoxin)

Before taking aspirin, tell your doctor if you also use digoxin. You may need dose adjustments or special tests in order to safely take both medications together. This combination may increase digoxin levels. You should notify your doctor if you have symptoms of nausea, loss of appetite, visual changes, slow pulse, or irregular heartbeats. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

digoxin omeprazole

Applies to: Lanoxicaps (digoxin) and Yosprala (aspirin / omeprazole)

Talk to your doctor before using digoxin together with omeprazole. Drugs known as proton pump inhibitors including omeprazole may increase the effects of digoxin. In the short-term, omeprazole can occasionally cause an increase in the blood levels of digoxin. You should seek immediate medical attention if you experience signs and symptoms that may indicate excessive effects of digoxin, such as nausea, vomiting, diarrhea, loss of appetite, visual disturbances (blurred vision; light halos around objects; green or yellow vision), or an abnormally fast or slow or uneven heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. If you continue to take omeprazole for a prolonged period (for example, several months to a year or more), you may develop a condition called hypomagnesemia, or low blood magnesium. Hypomagnesemia can increase the sensitivity of your heart to the effects of digoxin and cause toxicity even if your digoxin levels are within range. Let your doctor know if you develop symptoms of hypomagnesemia such as irregular heart rhythm, palpitations, muscle spasm, tremor, or seizures. In children, abnormal heart rhythm may cause fatigue, upset stomach, dizziness, and lightheadedness. If you are using an over-the-counter proton pump inhibitor medication such as Prilosec OTC, Zegerid OTC or Prevacid 24 HR, you should follow the directions on the package carefully. Do not use the medication more frequently or for a longer period than recommended on the label unless otherwise prescribed by your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

aspirin omeprazole

Applies to: Yosprala (aspirin / omeprazole) and Yosprala (aspirin / omeprazole)

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

aspirin food

Applies to: Yosprala (aspirin / omeprazole)

Ask your doctor before using aspirin together with ethanol. Do not drink alcohol while taking aspirin. Alcohol can increase your risk of stomach bleeding caused by aspirin. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

digoxin food

Applies to: Lanoxicaps (digoxin)

Information for this minor interaction is available on the professional version.

Minor

aspirin food

Applies to: Yosprala (aspirin / omeprazole)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.