Skip to main content

Drug Interactions between lamivudine / raltegravir and Uni-Lan II

This report displays the potential drug interactions for the following 2 drugs:

Edit list (add/remove drugs)

Interactions between your drugs

Major

aluminum hydroxide raltegravir

Applies to: Uni-Lan II (aluminum hydroxide / magnesium hydroxide / simethicone) and lamivudine / raltegravir

Aluminum hydroxide can interfere with the absorption of raltegravir, even if they are not taken at the same time. This may reduce the blood levels of raltegravir, which may make the medication less effective in treating HIV infection. You should avoid taking aluminum- or magnesium-containing antacids during treatment with raltegravir. Calcium carbonate antacids should be avoided with once-daily raltegravir, but may be used with other raltegravir products. Talk to a healthcare provider if you have any questions or concerns. Your doctor or pharmacist may be able to recommend alternatives that do not interact with raltegravir. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Major

magnesium hydroxide raltegravir

Applies to: Uni-Lan II (aluminum hydroxide / magnesium hydroxide / simethicone) and lamivudine / raltegravir

Magnesium hydroxide can interfere with the absorption of raltegravir, even if they are not taken at the same time. This may reduce the blood levels of raltegravir, which may make the medication less effective in treating HIV infection. You should avoid taking aluminum- or magnesium-containing antacids during treatment with raltegravir. Calcium carbonate antacids should be avoided with once-daily raltegravir, but may be used with other raltegravir products. Talk to a healthcare provider if you have any questions or concerns. Your doctor or pharmacist may be able to recommend alternatives that do not interact with raltegravir. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Switch to professional interaction data

Drug and food interactions

Major

aluminum hydroxide food

Applies to: Uni-Lan II (aluminum hydroxide / magnesium hydroxide / simethicone)

Citrate, or citric acid, can increase the absorption of aluminum hydroxide. This may lead to elevated blood levels of aluminum, particularly in individuals with reduced kidney function, since aluminum is primarily eliminated by the kidneys. Excess aluminum may deposit and cause problems in various tissues including bone, brain, heart, liver, muscles, and spleen. Over time, weak bones, bone pain, fractures, skeletal deformity, brain disorders, and anemia may develop. Talk to your doctor before using aluminum hydroxide if you have kidney impairment or are on hemodialysis. You should avoid or limit the consumption of citrate-containing foods and beverages (e.G., soft drinks, citrus fruits, fruit juices) during treatment with aluminum hydroxide. Be aware that some effervescent and dispersible drug formulations may also contain citrate and should be restricted as well. Even if you do not have kidney problems, it may be best to separate the dosing of aluminum hydroxide and citrate-containing products by 2 to 3 hours. Talk to a healthcare professional if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

When aluminum hydroxide is taken during enteral nutrition therapy (tube feeding), the tube may get clogged. Therefore, aluminum hydroxide should not be mixed with or given after high-protein tube feedings. The dose should be separated from the feeding by as much as possible, and the tube should be thoroughly flushed before administration of the dose.

Switch to professional interaction data

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


Report options

Loading...
QR code containing a link to this page

Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.