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Drug interactions between Kayexalate and sorbitol

Results for the following 2 drugs:
Kayexalate (sodium polystyrene sulfonate)

Interactions between your drugs


sodium polystyrene sulfonate ↔ sorbitol

Applies to:Kayexalate (sodium polystyrene sulfonate) and sorbitol

Talk to your doctor before using sodium polystyrene sulfonate together with sorbitol. When sodium polystyrene sulfonate is used with products containing sorbitol, damage to the tissues in the intestine may occur. The condition can be fatal in severe cases. Oral suspensions of some medications may contain sorbitol. If you are taking a liquid preparation of sorbitol or other medication, check the label to be sure it does not contain sorbitol. If you are not sure, ask your doctor or pharmacist. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions


sodium polystyrene sulfonate food

Applies to: Kayexalate (sodium polystyrene sulfonate)

Foods high in potassium such as orange juice and other fruit juices may reduce the effectiveness of sodium polystyrene sulfonate in treating your condition. Do not mix sodium polystyrene sulfonate in fruit juice or drink fruit juice with it. Also, sodium polystyrene sulfonate may interfere with the absorption of other medications that you take by mouth, including both prescription medications such as antibiotics, blood pressure/heart medications and blood thinners, and over-the-counter products such as antacids and laxatives. This can lead to lower blood levels and reduced effects if you take them too closely together with sodium polystyrene sulfonate. It is recommended that you separate the dosing of sodium polystyrene sulfonate from other oral medications by at least 3 hours whenever possible. This interval should be increased to 6 hours if you have gastroparesis or other conditions that cause delayed emptying of food from the stomach into the intestine. Talk to your doctor or pharmacist if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No therapeutic duplications were found for your selected drugs.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

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