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Orkambi (ivacaftor / lumacaftor) Drug Interactions

A total of 590 drugs (2725 brand and generic names) are known to interact with Orkambi (ivacaftor / lumacaftor).

  • 245 major drug interactions (1290 brand and generic names)
  • 339 moderate drug interactions (1423 brand and generic names)
  • 6 minor drug interactions (12 brand and generic names)

Show all medications in the database that may interact with Orkambi (ivacaftor / lumacaftor).

Check for interactions with Orkambi (ivacaftor / lumacaftor)

Type in a drug name and select a drug from the list.

Common medications checked in combination with Orkambi (ivacaftor / lumacaftor)

Orkambi (ivacaftor / lumacaftor) alcohol/food Interactions

There is 1 alcohol/food interaction with Orkambi (ivacaftor / lumacaftor)

Orkambi (ivacaftor / lumacaftor) disease Interactions

There are 3 disease interactions with Orkambi (ivacaftor / lumacaftor) which include:

Drug Interaction Classification

The classifications below are a general guideline only. It is difficult to determine the relevance of a particular drug interaction to any individual given the large number of variables.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.