IBU Interactions
There are 416 drugs known to interact with IBU (ibuprofen), along with 11 disease interactions, and 2 alcohol/food interactions. Of the total drug interactions, 99 are major, 302 are moderate, and 15 are minor.
- View all 416 medications that may interact with IBU
- View IBU alcohol/food interactions (2)
- View IBU disease interactions (11)
Most frequently checked interactions
View interaction reports for IBU (ibuprofen) and the medicines listed below.
- albuterol
- albuterol
- atorvastatin
- atorvastatin
- Benadryl (diphenhydramine)
- Benadryl (diphenhydramine)
- cyclobenzaprine
- cyclobenzaprine
- gabapentin
- gabapentin
- lisinopril
- lisinopril
- melatonin
- melatonin
- metformin
- metformin
- omeprazole
- omeprazole
- prednisone
- prednisone
- tramadol
- tramadol
- trazodone
- trazodone
- Tylenol (acetaminophen)
- Tylenol (acetaminophen)
- Vitamin D3 (cholecalciferol)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
- Xanax (alprazolam)
IBU alcohol/food interactions
There are 2 alcohol/food interactions with IBU (ibuprofen).
IBU disease interactions
There are 11 disease interactions with IBU (ibuprofen) which include:
- asthma
- fluid retention
- GI toxicity
- rash
- renal toxicities
- thrombosis
- PKU
- anemia
- hepatotoxicity
- hyperkalemia
- platelet aggregation inhibition
Report options
More about IBU (ibuprofen)
- IBU consumer information
- Compare alternatives
- Reviews (1)
- Latest FDA alerts (14)
- Side effects
- Dosage information
- During pregnancy
- Drug class: Nonsteroidal anti-inflammatory drugs
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
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Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.