Drug interactions between ibrutinib and rituximab
Interactions between your drugs
There were no interactions found in our database between ibrutinib and rituximab - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.
- Ibrutinib is in the drug class multikinase inhibitors.
- Ibrutinib is used to treat the following conditions:
- Rituximab is a member of the following drug classes: antirheumatics, CD20 monoclonal antibodies.
- Rituximab is used to treat the following conditions:
- Bullous Pemphigoid
- Chronic Lymphocytic Leukemia
- Diffuse Large B-Cell Lymphoma
- Evan's Syndrome
- Focal Segmental Glomerulosclerosis
- Follicular Lymphoma
- Granulomatosis with Polyangiitis
- Idiopathic Thrombocytopenic Purpura
- Mantle Cell Lymphoma
- Microscopic polyangiitis
- Non-Hodgkin's Lymphoma
- Pemphigus Vulgaris
- Rheumatoid Arthritis
Drug and food interactions
Applies to: ibrutinib
Ibrutinib should be taken once daily at approximately the same time everyday. Do not consume grapefruit, grapefruit juice, or Seville oranges unless directed otherwise by your doctor. Grapefruit and Seville oranges may significantly increase the blood levels of ibrutinib. This may increase the risk of side effects such as nausea, vomiting, diarrhea, abdominal pain, constipation, hemorrhage, kidney problems, and impaired bone marrow function resulting in low numbers of different types of blood cells. You may also be more likely to develop anemia, bleeding problems, or infections due to low blood cell counts. You should contact your doctor if you develop paleness, fatigue, dizziness, fainting, unusual bruising or bleeding, fever, chills, diarrhea, sore throat, muscle aches, shortness of breath, blood in phlegm, weight loss, red or inflamed skin, body sores, and pain or burning during urination. Also seek immediate medical attention if you experience signs and symptoms that may suggest kidney damage such as nausea, vomiting, loss of appetite, increased or decreased urination, sudden weight gain or weight loss, fluid retention, swelling, shortness of breath, muscle cramps, tiredness, weakness, dizziness, confusion, and irregular heart rhythm. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.