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Drug Interactions between hydrochlorothiazide / lisinopril and licorice

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

hydroCHLOROthiazide lisinopril

Applies to: hydrochlorothiazide / lisinopril and hydrochlorothiazide / lisinopril

Although hydroCHLOROthiazide and lisinopril are frequently combined together, their effects may be additive on lowering your blood pressure. You may need a dose adjustment or special tests to safely take both medications. Contact your doctor if you have a reduced heart rate, dizziness, fainting, or headaches. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

hydroCHLOROthiazide licorice

Applies to: hydrochlorothiazide / lisinopril and licorice

Ask your doctor before using hydroCHLOROthiazide together with licorice. Using these medications together may increase effects of hydroCHLOROthiazide and cause low blood potassium levels . This can cause fatigue, muscle pain or weakness, abdominal pain, hypoventilation, and irregular heartbeat. You may need a dose adjustment or special test if you use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

lisinopril licorice

Applies to: hydrochlorothiazide / lisinopril and licorice

Talk to your doctor before using licorice together with lisinopril. Products containing licorice (glycyrrhizic acid) can cause high blood pressure as well as salt and water retention, which may interfere with the effects of lisinopril. Generally, you should avoid or limit the consumption of licorice if you have high blood pressure, heart failure, pulmonary hypertension (high blood pressure in the vessels of the lung), or kidney disease. Check your food and medicine labels to be sure those products do not contain licorice or glycyrrhizic acid, which may be found in licorice-flavored chewing gum or candy, chewing tobacco, certain ethnic foods and beverages, and some herbal diuretics or laxatives. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Drug and food interactions

Moderate

lisinopril food

Applies to: hydrochlorothiazide / lisinopril

It is recommended that if you are taking lisinopril you should be advised to avoid moderately high or high potassium dietary intake. This can cause high levels of potassium in your blood. Do not use salt substitutes or potassium supplements while taking lisinopril, unless your doctor has told you to.

Moderate

hydroCHLOROthiazide food

Applies to: hydrochlorothiazide / lisinopril

HydroCHLOROthiazide and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Moderate

lisinopril food

Applies to: hydrochlorothiazide / lisinopril

Lisinopril and ethanol (alcohol) may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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