Drug interactions between Harvoni and Olysio
Interactions between your drugs
Applies to: Olysio (simeprevir) and Harvoni (ledipasvir / sofosbuvir)
Using simeprevir together with ledipasvir may significantly increase the blood levels of both medications, especially simeprevir. This may increase the risk of serious side effects such as skin rash and skin reactions to sunlight (photosensitivity), which may be severe enough to require hospitalization. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: Olysio (simeprevir)
Food significantly increases the absorption of simeprevir. You should take each dose of simeprevir with food. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.