Guaifenesin/hydrocodone/pseudoephedrine Interactions
There are 728 drugs known to interact with guaifenesin/hydrocodone/pseudoephedrine, along with 22 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 220 are major, 502 are moderate, and 6 are minor.
- View all 728 medications that may interact with guaifenesin/hydrocodone/pseudoephedrine
- View guaifenesin/hydrocodone/pseudoephedrine alcohol/food interactions (1)
- View guaifenesin/hydrocodone/pseudoephedrine disease interactions (22)
Most frequently checked interactions
View interaction reports for guaifenesin / hydrocodone / pseudoephedrine and the medicines listed below.
- Aceta (acetaminophen)
- Aceta (acetaminophen)
- Acetylsalicylic Acid (aspirin)
- Acetylsalicylic Acid (aspirin)
- Acidophilus (lactobacillus acidophilus)
- Acidophilus (lactobacillus acidophilus)
- Advil (ibuprofen)
- Advil (ibuprofen)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Allergy Sinus (chlorpheniramine / ibuprofen / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Cold and Sinus (ibuprofen / pseudoephedrine)
- Advil Migraine (ibuprofen)
- Advil Migraine (ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Advil PM (diphenhydramine / ibuprofen)
- Aleve (naproxen)
- Aleve (naproxen)
- Anacin (aspirin / caffeine)
- Anacin (aspirin / caffeine)
- Anacin Advanced Headache Formula (acetaminophen / aspirin / caffeine)
- Anacin Advanced Headache Formula (acetaminophen / aspirin / caffeine)
- Anacin Aspirin Free (acetaminophen)
- Anacin Aspirin Free (acetaminophen)
- Lasix (furosemide)
- Lasix (furosemide)
- Lopressor (metoprolol)
- Lopressor (metoprolol)
- Vitamin B12 (cyanocobalamin)
- Vitamin B12 (cyanocobalamin)
Guaifenesin/hydrocodone/pseudoephedrine alcohol/food interactions
There is 1 alcohol/food interaction with guaifenesin / hydrocodone / pseudoephedrine.
Guaifenesin/hydrocodone/pseudoephedrine disease interactions
There are 22 disease interactions with guaifenesin / hydrocodone / pseudoephedrine which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- cardiovascular disease
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
- GI narrowing
- PKU
- BPH
- diabetes
- glaucoma
Report options
More about guaifenesin / hydrocodone / pseudoephedrine
- guaifenesin/hydrocodone/pseudoephedrine consumer information
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
- En español
Related treatment guides
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
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Robitussin Nighttime Cough DM
Robitussin Nighttime Cough DM is used for cough, cough and nasal congestion
Dextromethorphan/guaifenesin/phenylephrine
Dextromethorphan/guaifenesin/phenylephrine systemic is used for cough and nasal congestion
Brompheniramine/dextromethorphan/pseudoephedrine
Brompheniramine/dextromethorphan/pseudoephedrine systemic is used for cough and nasal congestion
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.