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Drug interactions between grapefruit and Xalkori

Results for the following 2 drugs:
grapefruit
Xalkori (crizotinib)

Interactions between your drugs

There were no interactions found in our database between grapefruit and Xalkori - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

grapefruit

A total of 0 drugs are known to interact with grapefruit.

    Xalkori

    A total of 731 drugs are known to interact with Xalkori.

    Drug and food interactions

    Major

    crizotinib food

    Applies to: Xalkori (crizotinib)

    Do not consume grapefruit or grapefruit juice during treatment with crizotinib unless directed otherwise by your doctor. Grapefruit juice can increase the blood levels of crizotinib to dangerous levels and cause an irregular heart rhythm that may be serious. You should seek immediate medical attention if you develop sudden dizziness, lightheadedness, fainting, shortness of breath, or fast or pounding heartbeats during treatment with crizotinib. You may take crizotinib with or without food, but take it the same time each day. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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    Therapeutic duplication warnings

    No warnings were found for your selected drugs.

    Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

    Drug Interaction Classification

    The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No information available.

    Do not stop taking any medications without consulting your healthcare provider.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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