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Drug interactions between grapefruit and Tykerb

Results for the following 2 drugs:
grapefruit
Tykerb (lapatinib)

Interactions between your drugs

There were no interactions found in our database between grapefruit and Tykerb - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

grapefruit

A total of 0 drugs are known to interact with grapefruit.

    Tykerb

    A total of 690 drugs are known to interact with Tykerb.

    Drug and food interactions

    Moderate

    lapatinib food

    Applies to: Tykerb (lapatinib)

    Take lapatinib on an empty stomach 1 hour before or 1 hour after a meal unless otherwise directed by your doctor. This will make it easier for your body to absorb the medication. The lapatinib dose is administered once daily and should not be divided. The usual dose of lapatinib is equal to 5 tablets. You may swallow each tablet one at a time, but take the entire lapatinib dose at the same time each day. If you are receiving therapy with lapatinib you should be advised to avoid grapefruits and grapefruit juice. Grapefruit can raise the levels of lapatinib in your body and lead to dangerous side effects.

    Switch to professional interaction data

    Therapeutic duplication warnings

    No warnings were found for your selected drugs.

    Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

    Drug Interaction Classification

    The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No information available.

    Do not stop taking any medications without consulting your healthcare provider.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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