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Drug interactions between grapefruit and lurasidone

Results for the following 2 drugs:
grapefruit
lurasidone

Interactions between your drugs

There were no interactions found in our database between grapefruit and lurasidone - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

grapefruit

A total of 0 drugs are known to interact with grapefruit.

    lurasidone

    A total of 977 drugs (5510 brand and generic names) are known to interact with lurasidone.

    Drug and food interactions

    Major

    lurasidone food

    Applies to: lurasidone

    Avoid consuming grapefruit or grapefruit juice during treatment with lurasidone, as it may increase blood levels of the medication. This can increase the risk of side effects such as Parkinson-like symptoms, abnormal muscle movements, seizures, high blood sugar, diabetes, high cholesterol, weight gain, sex hormone irregularities, and heat-related disorders such as heat intolerance or heat stroke. In addition, you may be more likely to experience side effects associated with low blood pressure such as dizziness, lightheadedness, headache, flushing, fainting, and heart palpitations. You should also avoid the use of alcohol while being treated with lurasidone. Alcohol can increase the nervous system and blood-pressure lowering effects of lurasidone. You may experience increased drowsiness, dizziness, difficulty concentrating, and impairment in thinking and judgment. Talk to your doctor or pharmacist if you have any questions or concerns. Lurasidone should be taken with food consisting of at least 350 calories. Avoid driving or operating hazardous machinery until you know how the medication affects you, and use caution when getting up from a sitting or lying position.

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    Therapeutic duplication warnings

    No therapeutic duplications were found for your selected drugs.

    Drug Interaction Classification

    The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
    Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
    Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
    Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
    Unknown No information available.

    Do not stop taking any medications without consulting your healthcare provider.

    Further information

    Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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