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Drug Interactions between FS Shampoo and insulin glargine / lixisenatide

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

fluocinolone topical insulin glargine

Applies to: FS Shampoo (fluocinolone topical) and insulin glargine / lixisenatide

Some of the medication in fluocinolone topical may be absorbed into the bloodstream following application to your skin. When present in sufficient concentrations in the blood, steroids like fluocinolone topical can interfere with blood sugar control and reduce the effectiveness of insulin glargine and other diabetic medications. Although the absorption of most steroid preparations is limited when used as recommended in the product labeling, absorption may be increased under certain circumstances, such as: when the steroid is strong or highly potent; when the steroid is used for a longer duration; the person being treated is an infant or young child; or the area of skin being treated is large, inflamed, damaged (cut, scraped), thin (like the face), and/or covered with a dressing, wrapping or clothing. Blood sugar should be monitored closely in these situations. You may need a dose adjustment of insulin glargine and/or other diabetic medications if your blood sugar is affected. Talk to your health care provider if you have any questions or concerns. Do not exceed the recommended dose or frequency and duration of use when treated with products that contain steroids, including some over-the counter products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

fluocinolone topical lixisenatide

Applies to: FS Shampoo (fluocinolone topical) and insulin glargine / lixisenatide

Some of the medication in fluocinolone topical may be absorbed into the bloodstream following application to your skin. When present in sufficient concentrations in the blood, steroids like fluocinolone topical can interfere with blood sugar control and reduce the effectiveness of lixisenatide and other diabetic medications. Although the absorption of most steroid preparations is limited when used as recommended in the product labeling, absorption may be increased under certain circumstances, such as: when the steroid is strong or highly potent; when the steroid is used for a longer duration; the person being treated is an infant or young child; or the area of skin being treated is large, inflamed, damaged (cut, scraped), thin (like the face), and/or covered with a dressing, wrapping or clothing. Blood sugar should be monitored closely in these situations. You may need a dose adjustment of lixisenatide and/or other diabetic medications if your blood sugar is affected. Talk to your health care provider if you have any questions or concerns. Do not exceed the recommended dose or frequency and duration of use when treated with products that contain steroids, including some over-the counter products. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

insulin glargine lixisenatide

Applies to: insulin glargine / lixisenatide and insulin glargine / lixisenatide

Using lixisenatide together with insulin glargine can increase the risk of hypoglycemia, or low blood sugar. You may need a dose adjustment or more frequent monitoring of your blood sugar to safely use both medications. Let your doctor know if you experience hypoglycemia during treatment. Symptoms of hypoglycemia include headache, dizziness, drowsiness, nervousness, confusion, tremor, nausea, hunger, weakness, perspiration, palpitation, and rapid heartbeat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

insulin glargine food

Applies to: insulin glargine / lixisenatide

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

lixisenatide food

Applies to: insulin glargine / lixisenatide

Lixisenatide may affect the absorption of other medications that you take by mouth. In some cases, this may affect how well and/or how fast those medications work, or it may make no difference. Talk to a healthcare provider if you have any questions or concerns, and contact your doctor if your symptoms worsen or your condition changes. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.