Drug Interactions between fluticasone / umeclidinium / vilanterol and mifepristone

Using miFEPRIStone together with fluticasone is generally not recommended. Combining these medications may significantly reduce the effects of fluticasone. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

MiFEPRIStone may increase the absorption of vilanterol from the lungs into the blood stream. You may be more likely to experience cardiovascular side effects such as palpitation, chest pain, irregular heart beat, increased heart and pulse rates, and blood pressure elevations. Talk to your doctor before using these medications if you have a history of heart disease or high blood pressure, or if you have other questions or concerns. The risk of side effects also increases with overuse of vilanterol. Therefore, you should not exceed the dose or frequency of use prescribed by your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

Information for this minor interaction is available on the professional version.