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Drug Interactions between Floxin IV and sodium bicarbonate / sodium citrate

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

ofloxacin sodium bicarbonate

Applies to: Floxin IV (ofloxacin) and sodium bicarbonate / sodium citrate

Talk to your doctor before using sodium bicarbonate together with ofloxacin. Sodium bicarbonate can change the acidity of your urine, which may cause ofloxacin to crystallize and form stones. This may also occur if you are dehydrated, so you should drink plenty of fluids during treatment with ofloxacin. Let your doctor know if you experience flank pain, painful urination, or blood in the urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

ofloxacin sodium citrate

Applies to: Floxin IV (ofloxacin) and sodium bicarbonate / sodium citrate

Talk to your doctor before using sodium citrate together with ofloxacin. Sodium citrate can change the acidity of your urine, which may cause ofloxacin to crystallize and form stones. This may also occur if you are dehydrated, so you should drink plenty of fluids during treatment with ofloxacin. Let your doctor know if you experience flank pain, painful urination, or blood in the urine. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

ofloxacin food

Applies to: Floxin IV (ofloxacin)

Ofloxacin and multivitamin with minerals should not be taken orally at the same time. Products that contain magnesium, aluminum, calcium, iron, and/or other minerals may interfere with the absorption of ofloxacin into the bloodstream and reduce its effectiveness. If possible, it may be best to avoid taking multivitamin with minerals while you are being treated with ofloxacin. Otherwise, ofloxacin should be taken 2 to 4 hours before or 4 to 6 hours after a multivitamin with minerals dose, ofloxacin should be taken at least 2 hours before and not less than 6 hours after Suprep Bowel Prep (magnesium/potassium/sodium sulfates), or ofloxacin and multivitamin with minerals should be taken as directed by your healthcare provider. Talk to your healthcare provider if you are unsure whether your medications contain something that could potentially interact or if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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