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Drug Interactions between Evotaz and Nydrazid

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

isoniazid atazanavir

Applies to: Nydrazid (isoniazid) and Evotaz (atazanavir / cobicistat)

Isoniazid may increase the blood levels and effects of atazanavir. This may increase the risk and/or severity of side effects such as jaundice, kidney stones, gallstones, high blood sugar, diabetes, and irregular heartbeat. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you develop yellowing of the skin or eyes, pain in your side or lower back, painful urination, blood in your urine, abdominal pain or tenderness, or sudden dizziness, lightheadedness, fainting, or a slow heart rate during treatment with these medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

isoniazid food

Applies to: Nydrazid (isoniazid)

Food decreases the levels of isoniazid in your body. Take isoniazid on an empty stomach at least 1 hour before or 2 hours after a meal. This will make it easier for your body to absorb the medication. If nausea occurs, ask your doctor if you can take isoniazid with food. Avoid alcohol while taking isoniazid. Alcohol may increase the risk of damage to the liver during isoniazid treatment. Alcohol can also cause isoniazid side effects to get worse. Contact your doctor if you experience flushing, chills, headache, nausea, vomiting, and diarrhea.

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Moderate

atazanavir food

Applies to: Evotaz (atazanavir / cobicistat)

Food can enhance the levels of atazanavir in your body. To ensure maximal oral absorption, atazanavir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer