Drug Interactions between EpiPen Auto-Injector and LMX Plus
This report displays the potential drug interactions for the following 2 drugs:
- EpiPen Auto-Injector (epinephrine)
- LMX Plus (lidocaine topical)
Interactions between your drugs
No interactions were found between EpiPen Auto-Injector and LMX Plus. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
EpiPen Auto-Injector
A total of 227 drugs are known to interact with EpiPen Auto-Injector.
- Epipen auto-injector is in the following drug classes: adrenergic bronchodilators, catecholamines, vasopressors.
- Epipen auto-injector is used to treat the following conditions:
LMX Plus
A total of 47 drugs are known to interact with LMX Plus.
- Lmx plus is in the drug class topical anesthetics.
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Lmx plus is used to treat the following conditions:
- Anesthesia (off-label)
- Burns, External
- Local Anesthesia
- Pain
- Pruritus
- Sunburn
Drug and food interactions
EPINEPHrine food
Applies to: EpiPen Auto-Injector (epinephrine)
MONITOR: Coadministration of two or more sympathomimetic agents may increase the risk of adverse effects such as nervousness, irritability, and increased heart rate. Central nervous system (CNS) stimulants, particularly amphetamines, can potentiate the adrenergic response to vasopressors and other sympathomimetic agents. Additive increases in blood pressure and heart rate may occur due to enhanced peripheral sympathetic activity.
MANAGEMENT: Caution is advised if two or more sympathomimetic agents are coadministered. Pulse and blood pressure should be closely monitored.
References
- Rosenblatt JE, Lake CR, van Kammen DP, Ziegler MG, Bunney WE Jr (1979) "Interactions of amphetamine, pimozide, and lithium on plasma norepineophrine and dopamine-beta-hydroxylase in schizophrenic patients." Psychiatry Res, 1, p. 45-52
- Cavanaugh JH, Griffith JD, Oates JA (1970) "Effect of amphetamine on the pressor response to tyramine: formation of p-hydroxynorephedrine from amphetamine in man." Clin Pharmacol Ther, 11, p. 656
- (2001) "Product Information. Adderall (amphetamine-dextroamphetamine)." Shire Richwood Pharmaceutical Company Inc
- (2001) "Product Information. Tenuate (diethylpropion)." Aventis Pharmaceuticals
- (2001) "Product Information. Sanorex (mazindol)." Novartis Pharmaceuticals
- (2001) "Product Information. Focalin (dexmethylphenidate)." Mikart Inc
- (2002) "Product Information. Strattera (atomoxetine)." Lilly, Eli and Company
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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