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Drug interactions between emtricitabine / tenofovir alafenamide and rilpivirine

Results for the following 2 drugs:
emtricitabine/tenofovir alafenamide

Interactions between your drugs

There were no interactions found in our database between emtricitabine / tenofovir alafenamide and rilpivirine - however, this does not necessarily mean no interactions exist. Always consult with your doctor or pharmacist.

emtricitabine / tenofovir alafenamide

A total of 250 drugs are known to interact with emtricitabine / tenofovir alafenamide.


A total of 406 drugs are known to interact with rilpivirine.

Drug and food interactions


rilpivirine food

Applies to: rilpivirine

Food significantly increases the absorption of rilpivirine. You should take each dose of rilpivirine with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Grapefruit juice can also increase the absorption of rilpivirine.

Switch to professional interaction data


tenofovir food

Applies to: emtricitabine / tenofovir alafenamide

Consumer information for this minor interaction is not currently available. Some minor drug interactions may not be clinically relevant in all patients. Minor drug interactions do not usually cause harm or require a change in therapy. However, your healthcare provider can determine if adjustments to your medications are needed.

For clinical details see professional interaction data.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

Drug Interaction Classification

The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No information available.

Do not stop taking any medications without consulting your healthcare provider.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.