Drug interactions between eletriptan and erythromycin
Interactions between your drugs
erythromycin ↔ eletriptan
Applies to:erythromycin and eletriptan
Erythromycin may significantly increase the blood levels and effects of eletriptan, which in some cases can lead to excessive narrowing of blood vessels in the body. This can reduce blood flow to vital organs and increase the risk of rare but serious side effects such as high blood pressure, heart attack, stroke, and gangrene (death of tissues, usually in the arm or leg, that may require surgical amputation). In general, you should not use eletriptan until at least 72 hours after the last dose of eletriptan. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if you experience numbness, tingling, chest pain or tightness, shortness of breath, or irregular heartbeat, as these may be signs and symptoms of excessive eletriptan levels. Do not take larger doses or use the drug more frequently than prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
Applies to: erythromycin
Food decreases the levels of erythromycin in your body. Take erythromycin on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication. However, some erythromycin products may be taken without regard to meals. Ask your healthcare provider about your particular prescription if you are uncertain of how to take it. Grapefruits and grapefruit juice may increase erythromycin levels but how this may affect you is not known. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.
Therapeutic duplication warnings
No therapeutic duplications were found for your selected drugs.
Drug Interaction Classification
|Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.|
|Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.|
|Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.|
|No information available.|
Do not stop taking any medications without consulting your healthcare provider.
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.