Drug Interactions between eculizumab and immune globulin intravenous and subcutaneous
This report displays the potential drug interactions for the following 2 drugs:
- eculizumab
- immune globulin intravenous and subcutaneous
Interactions between your drugs
eculizumab immune globulin intravenous and subcutaneous
Applies to: eculizumab and immune globulin intravenous and subcutaneous
According to the prescribing information for eculizumab, intravenous immunoglobulin (IVIg) treatment may interfere with the endosomal neonatal Fc receptor (FcRn) recycling mechanism of monoclonal antibodies such as eculizumab, which may lead to decreased serum concentrations of eculizumab. The clinical significance is unknown. Drug interaction studies have not been conducted with eculizumab in patients treated with IVIg.
References (3)
- Cerner Multum, Inc. "UK Summary of Product Characteristics."
- (2007) "Product Information. Soliris (eculizumab)." Alexion Pharmaceuticals Inc
- Cerner Multum, Inc. "Australian Product Information."
Drug and food interactions
No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
Check Interactions
To view an interaction report containing 4 (or more) medications, please sign in or create an account.
Save Interactions List
Sign in to your account to save this drug interaction list.