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Drug Interactions between dolutegravir / rilpivirine and E.E.S.-400 Filmtab

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

erythromycin rilpivirine

Applies to: E.E.S.-400 Filmtab (erythromycin) and dolutegravir / rilpivirine

Talk to your doctor before using rilpivirine together with erythromycin. Combining these medications may increase the blood levels and effects of rilpivirine. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

erythromycin dolutegravir

Applies to: E.E.S.-400 Filmtab (erythromycin) and dolutegravir / rilpivirine

Information for this minor interaction is available on the professional version.

Drug and food interactions

Moderate

erythromycin food

Applies to: E.E.S.-400 Filmtab (erythromycin)

Food decreases the levels of erythromycin in your body. Take erythromycin on an empty stomach at least 30 minutes before or 2 hours after a meal. This will make it easier for your body to absorb the medication. However, some erythromycin products may be taken without regard to meals. Ask your healthcare provider about your particular prescription if you are uncertain of how to take it. Grapefruits and grapefruit juice may increase erythromycin levels but how this may affect you is not known. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor.

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Moderate

rilpivirine food

Applies to: dolutegravir / rilpivirine

Food significantly increases the absorption of rilpivirine. You should take each dose of rilpivirine with a meal. Taking it on an empty stomach may lead to inadequate blood levels and reduced effectiveness of the medication. Grapefruit juice can also increase the absorption of rilpivirine and should preferably be avoided.

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Minor

dolutegravir food

Applies to: dolutegravir / rilpivirine

Information for this minor interaction is available on the professional version.

Minor

erythromycin food

Applies to: E.E.S.-400 Filmtab (erythromycin)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

See also

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer