Diphenhydramine topical Interactions

There are 4 drugs known to interact with diphenhydramine topical. Of the total drug interactions, 2 are major, and 2 are moderate.

Medications known to interact with diphenhydramine topical

Note: Showing generic names only.

Include all brand names and combination drug names.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major	Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate	Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor	Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown	No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

How to Prevent Deadly Drug Interactions

Some mixtures of medications can lead to serious and even fatal consequences.

Here are 9 ways to stay safe

Drug Status

Availability Over the counter OTC

Pregnancy & Lactation Risk data available

CSA Schedule* Not a controlled drug N/A

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