Sleep Tablets Interactions
There are 449 drugs known to interact with Sleep Tablets (diphenhydramine), along with 8 disease interactions, and 1 alcohol/food interaction. Of the total drug interactions, 15 are major, 431 are moderate, and 3 are minor.
- View all 449 medications that may interact with Sleep Tablets
- View Sleep Tablets alcohol/food interactions (1)
- View Sleep Tablets disease interactions (8)
Most frequently checked interactions
View interaction reports for Sleep Tablets (diphenhydramine) and the medicines listed below.
- acetaminophen
- amlodipine
- aspirin
- atorvastatin
- biotin
- bupropion
- buspirone
- clonazepam
- cyclobenzaprine
- Cymbalta (duloxetine)
- Flexeril (cyclobenzaprine)
- gabapentin
- hydrochlorothiazide
- hydroxyzine
- ibuprofen
- levothyroxine
- lisinopril
- losartan
- melatonin
- metformin
- omeprazole
- pantoprazole
- tramadol
- trazodone
- Tylenol (acetaminophen)
- venlafaxine
- Vitamin B12 (cyanocobalamin)
- Vitamin C (ascorbic acid)
- Vitamin D3 (cholecalciferol)
- Xanax (alprazolam)
Sleep Tablets alcohol/food interactions
There is 1 alcohol/food interaction with Sleep Tablets (diphenhydramine).
Sleep Tablets disease interactions
There are 8 disease interactions with Sleep Tablets (diphenhydramine) which include:
- depression
- anticholinergic effects
- asthma/COPD
- cardiovascular
- renal/liver disease
- glaucoma
- liver disease
- resp depression
Report options
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More about Sleep Tablets (diphenhydramine)
Drug Interaction Classification
| Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
| Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
| Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
| No interaction information available. |
See also:
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.